CXCL9 anticorps (PE)

N° du produit ABIN2662706

Cet anticorps anti-CXCL9 est un anticorps Souris Monoclonal détectant CXCL9 dans FACS. Adapté pour Humain.

Aperçu rapide pour CXCL9 anticorps (PE) (ABIN2662706)

Antigène: CXCL9 (gamma-Interferon-Induced Monokine (CXCL9))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CXCL9 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Clone: J1015E10

Détail du produit anti-CXCL9 anticorps (PE)

Purification: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Isotype: IgG2a kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur CXCL9

Antigène: CXCL9 (gamma-Interferon-Induced Monokine (CXCL9))

Autre désignation: CXCL9

Sujet: Chemokine (C-X-C motif) ligand 9 (CXCL9), also known as monokine induced by gamma interferon (MIG), is a small cytokine belonging to the non-ELR (lacking a Glu-Leu-Arg motif in the N-terminal region) motif CXC chemokines. CXCL9 is one of the ligands to share its receptor, CXCR3, with other two CXC chemokine family members, CXCL10 and CXCL11, through different binding fashions. The rank order of binding affinity is CXCL11>CXCL10>CXCL9. Some studies have revealed that these ligands have redundant functions in vivo, other studies have demonstrated that the three CXCR3 ligands can collaborate and even compete with each other. CXCL9 is mainly produced by activated macrophages and some cancer cells. Functioning as a chemoattractant, CXCL9 attracts CXCR3-expressing cells (such as a subset of circulating T cells, B cells, and natural killer cells) into inflammatory sites. Like other chemokines, CXCL9 is also able to elicit intracellular calcium flux and activate PI3K and MAPK. It participates in multiple immune and inflammatory responses by affecting cell growth, movement, or activation.