Aperçu rapide pour TCR V beta 12 anticorps (PE) (ABIN2662863)
Antigène
TCR V beta 12
Reactivité
Souris
Hôte
Souris
Clonalité
Monoclonal
Conjugué
Cet anticorp TCR V beta 12 est conjugé à/à la PE
Application
Flow Cytometry (FACS)
Clone
MR11-1
Purification
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
Isotype
IgG1 kappa
Indications d'application
Optimal working dilution should be determined by the investigator.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Protect from prolonged exposure to light. Do not freeze.
Stock
4 °C
Stockage commentaire
The antibody solution should be stored undiluted between 2°C and 8°C.
Antigène
TCR V beta 12
Autre désignation
TCR V Beta12
Sujet
T cell receptor Vβ12 (TCR Vβ12) is a variant of TCR β chain and, along with TCR α chain, forms the TCR heterodimer. In association with the CD3 complex, TCR α/β is responsible for antigen recognition through interaction with MHC-peptide complex to initiate the T cell-mediated immune responses. The MR11-1 antibody reacts with the Vβ 12 TCR of mice bearing the b haplotype. It has been reported that Mtv-8 and Mtv-9 cause clonally deletion of Vβ12+ T cells.