GPR77 anticorps (PE)

N° du produit ABIN2662916

Cet anticorps anti-GPR77 Monoclonal Souris conjugué à PE (Clone 1D9-M12) (ABIN2662916) détecte spécifiquement GPR77 dans IHC, FACS et BR. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour GPR77 anticorps (PE) (ABIN2662916)

Antigène: GPR77 (G Protein-Coupled Receptor 77 (GPR77))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GPR77 est conjugé à/à la PE

Application: Immunohistochemistry (IHC), Flow Cytometry (FACS), Blocking Reagent (BR)

Clone: 1D9-M12

Détail du produit anti-GPR77 anticorps (PE)

Purification: The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Isotype: IgG2a kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur GPR77

Antigène: GPR77 (G Protein-Coupled Receptor 77 (GPR77))

Autre désignation: C5L2

Sujet: C5L2 (C5a receptor-like 2) is a seven-transmembrane orphan receptor, also known as GPR77, which shares significant homology to C5a receptor (CD88). But it is a decoy receptor without G-protein coupling. C5L2 is co-expressed with C5aR on many kinds of cells, such as neutrophils, immature dendritic cells, mast cells, macrophages, and astrocytes. C5L2 binds C5a with similar high affinity as C5aR and relatively higher affinity for C5a-des-Arg than with C5aR. Clone 1D9-M12 is known to block C5a binding to C5L2, but does not react with C5a receptor.