IFNGR1 anticorps (PE)

N° du produit ABIN2662963

Détail du produit anti-IFNGR1 anticorps (PE)

Antigène: IFNGR1 (Interferon gamma Receptor 1 (IFNGR1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IFNGR1 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Purification: The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Clone: GIR-94

Isotype: IgG2b kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur IFNGR1

Antigène: IFNGR1 (Interferon gamma Receptor 1 (IFNGR1))

Autre désignation: CD119 (IFNGR1 Produits)

Synonymes: anticorps CD119, anticorps IFNGR, anticorps IFN-gammaR, anticorps Ifgr, anticorps Ifngr, anticorps Nktar, anticorps IFNGR1, anticorps MGC129098, anticorps ifngr1, anticorps MGC194858, anticorps MGC194873, anticorps zgc:194858, anticorps cd119, anticorps ifngr, anticorps DKFZp469K1232, anticorps interferon gamma receptor 1, anticorps cytokine receptor family member B17, anticorps IFNGR1, anticorps Ifngr1, anticorps crfb17, anticorps ifngr1

Sujet: CDw119 is a 90-100 kD type I transmembrane protein, also known as IFN-γ R α chain or IFN-γRI. The IFN-γ receptor is a complex of a high affinity IFN-γ-binding chain (aka, IFN-γ R α chain) and a second accessory protein required for signal transduction known as IFN-γ R β chain. The IFN-γ R α chain is a member of the class II cytokine receptor family. Binding of IFN-γ induces receptor dimerization and internalization. Signal transduction involves Jak1 and Jak2 protein kinases and involves STAT1 activation. The IFN-γ receptor is expressed at moderate levels on virtually every cell with the exception of erythrocytes.

Pathways: Interferon-gamma Pathway