VPREB1 anticorps (PE)

N° du produit ABIN2663102

Détail du produit anti-VPREB1 anticorps (PE)

Antigène: VPREB1 (Pre-B Lymphocyte 1 (VPREB1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp VPREB1 est conjugé à/à la PE

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Purification: The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Clone: HSL96

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur VPREB1

Antigène: VPREB1 (Pre-B Lymphocyte 1 (VPREB1))

Autre désignation: CD179a (VPREB1 Produits)

Synonymes: anticorps IGI, anticorps IGVPB, anticorps VPREB, anticorps VpreB, anticorps CD179a, anticorps Vpreb-1, anticorps V-set pre-B cell surrogate light chain 1, anticorps immunoglobulin iota chain, anticorps immunoglobulin iota chain-like, anticorps pre-B lymphocyte 1, anticorps pre-B lymphocyte gene 1, anticorps VPREB1, anticorps LOC698810, anticorps LOC486411, anticorps Vpreb1

Sujet: CD179a is an 18 kD Ig V-like protein expressed on pro-B and early pre-B cells. It is a member of the Ig gene superfamily, known as VpreB, VPREB1, and IGVPB. CD179a noncovalently associates with CD179b (λ5) to form a surrogate light (SL) chain. The SL chain is complexed with membrane bound IgM heavy (μH) chain and CD79a/CD79b heterodimer to form the pre-B-cell receptor (PreBCR) complex. The function of CD179a/CD179b is still under investigation though it has been reported that the pre-BCR complex plays a critical role in B cell development.

Pathways: Production of Molecular Mediator of Immune Response, Regulation of Cell Size