CD180 anticorps (PE)

N° du produit ABIN2663107

Détail du produit anti-CD180 anticorps (PE)

Antigène: CD180 (CD180 Molecule (CD180))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD180 est conjugé à/à la PE

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Réactivité croisée: Babouin, Cynomolgus, Macaque rhésus

Purification: The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Clone: MHR73-11

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur CD180

Antigène: CD180 (CD180 Molecule (CD180))

Autre désignation: CD180 (CD180 Produits)

Synonymes: anticorps Ly78, anticorps CD180, anticorps LY64, anticorps RP105, anticorps F630107B15, anticorps CD180 molecule, anticorps CD180 antigen, anticorps Cd180, anticorps CD180

Sujet: CD180, also known as RP105, is a 105 kD member of the toll-like receptor (TLR) family and is expressed on most B cells, monocytes/macrophages and dendritic cells. The TLR family's structural characteristics are critically involved in protein-protein signaling interactions leading to the activation of the innate immune system. Additionally, MD-1, a secretory protein, associates with CD180 (RP105) at the cell surface and this complex, in conjunction with TLR4, recognizes bacterial LPS. The human CD180 (RP105) gene maps to 5q12. The MHR73-11 antibody is able to activate B cells and to protect against irradiation- or dexamethasone-induced apoptosis.

Pathways: Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades