ICOSLG anticorps (PE)

N° du produit ABIN2663282

Cet anticorps anti-ICOSLG Monoclonal Rat conjugué à PE (Clone HK5-3) (ABIN2663282) détecte spécifiquement ICOSLG dans ELISA (Detection). L’anticorps est réactif avec des échantillons de Souris.

Aperçu rapide pour ICOSLG anticorps (PE) (ABIN2663282)

Antigène: ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp ICOSLG est conjugé à/à la PE

Application: ELISA (Detection)

Clone: HK5-3

Détail du produit anti-ICOSLG anticorps (PE)

Purification: The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Isotype: IgG2a kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.2 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur ICOSLG

Antigène: ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))

Autre désignation: CD275

Sujet: CD275 is a 40 kD protein, also known as ICOS ligand, B7-RP1, B7-H2, and B7h. It is a member of the immunoglobulin receptor superfamily expressed on splenic B cells, dendritic cells, and macrophages. The expression of this antigen is increased by TNF-α stimulation and is highly upregulated by local inflammation. B7RP1 binds to ICOS and co-stimulates T cell and B cell responses. Two isoforms of this protein have been reported to occur as a result of alternative splicing. These isoforms show differential tissue distribution.

Pathways: Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation