TCR V Alpha24-J Alpha18 anticorps (PE)

N° du produit ABIN2663907

Cet anticorps Souris Monoclonal détecte spécifiquement dans BCA. Il présente une réactivité envers Humain.

Aperçu rapide pour TCR V Alpha24-J Alpha18 anticorps (PE) (ABIN2663907)

Antigène: TCR V Alpha24-J Alpha18

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: PE

Application: Biochemical Assay (BCA)

Clone: 6B11

Détail du produit

Réactivité croisée: Pigtailed Macaque, Sooty mangabey (Cercocebus atys), Macaque rhésus

Purification: The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détail du antigène

Antigène: TCR V Alpha24-J Alpha18

Sujet: Encoded by the TCR Vα24-Jα18 germline configuration, Vα24-JαQ is expressed on a subset of NKT cells, namely invariant NKT (iNKT). Vα 24-JαQ TCR interacts with the glycolipid loaded MHC class 1b molecule CD1d, inducing activation and subsequent cytokine production. iNKT cells have been implicated in immune regulation, tumor surveillance, and host response to pathogens. While iNKT cells occur at low frequency in the blood, assorted chemokines contribute to their tissue homing potential.