TCR V Beta13.2 anticorps (PE)

N° du produit ABIN2663914

L’anticorps anti-TCR V Beta13.2 Monoclonal Souris est utilisé pour la détection de TCR V Beta13.2 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour TCR V Beta13.2 anticorps (PE) (ABIN2663914)

Antigène: TCR V Beta13.2

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: PE

Application: Western Blotting (WB)

Clone: H132

Détail du produit

Purification: The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détail du antigène

Antigène: TCR V Beta13.2

Sujet: The Vβ13.2 TCR is a variant of the TCR β chain. It belongs to Ig superfamily and is expressed by a subset of peripheral blood T cells and some T cell clones. Vβ expression in humans and mice has been used to study the effects of superantigens and also to examine the repertoires of T cells involved in inflammatory and autoimmune disease. It is reported that Vβ13.2 TCRs possess very unusually long β-chain CDR3 regions and are expressed on CTL specific for the immunodominant human HLA-B8-restricted HIV-1 nef epitope, FLKEKGGL (FL8). CTL expressing V β13.2 TCRs tolerate naturally arising viral variants in the FL8 epitope that escape recognition by other CTL. The clone H132 recognizes the Vβ13.2 allele product but does not react with the Vβ13.1, 13.3, 13.5 and 13.6 allele products of the Vβ13 subfamily.