The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
Clone
GL2
Isotype
IgG2 kappa
Indications d'application
Optimal working dilution should be determined by the investigator.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Protect from prolonged exposure to light. Do not freeze.
Stock
4 °C
Stockage commentaire
The antibody solution should be stored undiluted between 2°C and 8°C.
Antigène
V delta 4 TCR
Autre désignation
TCR V Delta4
Sujet
Lymphocytes expressing γ/δ antigen receptors constitute a minor population in lymphoid tissue, but a major population within epidermal, gastraintestine, and vaginouterine epithelia. Gamma/Delta T cells are involved in immunological surveillance of epithelia separating the external environment from the internal milieu. The GL2 antibody reacts with Vδ4 T-cell receptor (TCR) bearing T cells, which are the predominant γ/δ T cells in intestinal epithelium (γ/δ IEL). Gamma/delta T cells has been found in mammary glad as well. The frequency of Vδ4 TCR-bearing cells varies among inbred strains of mice.