SIRPA anticorps

N° du produit ABIN2664292

L’anticorps anti-SIRPA Monoclonal Souris est utilisé pour la détection de SIRPA dans des échantillons de Rat. Il a été validé pour FACS, IHC et IF.

Aperçu rapide pour SIRPA anticorps (ABIN2664292)

Antigène: SIRPA (Signal-Regulatory Protein alpha (SIRPA))

Reactivité: Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SIRPA est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)

Clone: OX-41

Détail du produit anti-SIRPA anticorps

Purification: The antibody was purified by affinity chromatography.

Isotype: IgG2a kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur SIRPA

Antigène: SIRPA (Signal-Regulatory Protein alpha (SIRPA))

Autre désignation: CD172a

Sujet: Rat CD172a, also known as a signal-regulatory protein α (SIRPα), is a 75-110 kD transmembrane glycoprotein involved in the receptor tyrosine kinase coupled signaling pathway. It belongs to the Ig superfamily primarily expressed on monocytes/macrophages, granulocytes, dendritic cells and neurons. CD172a serves as a substrate of activated receptor ttyrosine kinases (RTKs). The interaction of the CD172a intracellular domain with SHP-1 and SHP-2 displays negative signaling in the regulation of leukocyte adhesion and transmigration, T cell activation, macrophage fusion and phagocytosis. CD47 (IAP) is an extracellular ligand for CD172a.