CCR3 anticorps
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- Antigène Voir toutes CCR3 Anticorps
- CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CCR3 est non-conjugé
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Application
- Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Purification
- The antibody was purified by affinity chromatography.
- Clone
- 5E8
- Isotype
- IgG2b kappa
- Top Product
- Discover our top product CCR3 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Antigène
- CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))
- Autre désignation
- CD193 (CCR3 Produits)
- Synonymes
- anticorps CC-CKR-3, anticorps CD193, anticorps CKR3, anticorps CMKBR3, anticorps CC-CKR3, anticorps Cmkbr1l2, anticorps Cmkbr3, anticorps C-C motif chemokine receptor 3, anticorps chemokine (C-C motif) receptor 3, anticorps CCR3, anticorps Ccr3
- Sujet
- CD193, also known as CC-chemokine receptor 3 (CCR3), CC CKR3, MIP1-alpha receptor like-2, and eotaxin receptor, is a member of the G protein-coupled seven transmembrane receptors family. It binds to the CC chemokines eotaxin, eotaxin-2, and eotaxin-3 with high affinity. CCR3 has also been reported to bind RANTES, MCP-3, and MCP-4 with low affinity. CCR3 receptor is expressed on human eosinophils, basophils, mast cells, mononuclear phagocytes, platelets, CD34+ hematopoietic progenitor cells, Th2-like lymphocytes, and keratinocytes. CCR3 is thought to play a role in allergic diseases such as bronchial asthma and allergic rhinitis. CCR3 is a co-receptor for HIV-1 and HIV-2, and the binding of eotaxin with CCR3 has been shown to inhibit HIV infection in some cell types.
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