CD213alpha1 anticorps

N° du produit ABIN2664399

Cet anticorps Souris Monoclonal détecte spécifiquement CD213alpha1 dans ICFC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour CD213alpha1 anticorps (ABIN2664399)

Antigène: CD213alpha1

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Intracellular Flow Cytometry (ICFC)

Clone: SS12B

Détail du produit

Purification: The antibody was purified by affinity chromatography.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détail du antigène

Antigène: CD213alpha1

Sujet: CD213α1, also known as IL-13Rα1, is a subunit of the IL-13R complex. It can heterodimerize with IL-4R and bind IL-13 with high affinity. IL-13Rα1 by itself binds IL-13 with low affinity compared to IL-13Rα2. It is a 48.7 kD, single pass type I membrane protein. It is expressed at low levels on myeloid cells and on activated T and B cells and Th17 cells. It interacts with TYK2 and may lead to activation of JAK1, STAT3, and STAT6 that is induced by IL-13 and IL-4. It has been implicated to have a role in asthma and allergic responses.