CD37 anticorps

N° du produit ABIN2664634

L’anticorps Rat Monoclonal anti-CD37 a été validé pour WB, IHC et IP. Il convient pour détecter CD37 dans des échantillons de Souris.

Aperçu rapide pour CD37 anticorps (ABIN2664634)

Antigène: CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp CD37 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Clone: Duno85

Détail du produit anti-CD37 anticorps

Purification: The antibody was purified by affinity chromatography.

Isotype: IgG2a kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur CD37

Antigène: CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))

Autre désignation: CD37

Sujet: CD37, also known as Tspan26 is a 40-60 kD member of the tetraspanin (TM4SF) family, with two extracellular regions and both termini in the cytoplasm. CD37 is highly expressed on mature B cells and is also expressed on T cells, monocytes, macrophages, and neutrophils, and dendritic cells to a lesser extent. CD37 forms complexes in the cell membrane with CD53, CD81, CD82, MHC class II and dectin 1. CD37 is essential for B cell survival, regulates T cell proliferation, IgA production, and is involved in dendritic cell migration. CD37 has been described as a promising target in the treatment of B cell malignancies.

Pathways: Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response