CD6 anticorps

N° du produit ABIN2664783

Cet anticorps Rat Monoclonal détecte spécifiquement CD6 dans FACS. Il présente une réactivité envers Souris.

Aperçu rapide pour CD6 anticorps (ABIN2664783)

Antigène: CD6

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp CD6 est non-conjugé

Application: Flow Cytometry (FACS)

Clone: OX-129

Détail du produit anti-CD6 anticorps

Purification: The antibody was purified by affinity chromatography.

Isotype: IgG2a kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur CD6

Antigène: CD6

Autre désignation: CD6

Sujet: CD6, a 100 kD monomeric T cell surface glycoprotein, is a member of the scavenger receptor cysteine-rich protein superfamily. It is expressed on mouse thymocytes and splenic T cells and neurons, but not on splenic B cells. CD6 has a long cytoplasmic tail in mice, with two proline-rich domains that interact with the -SH3 domain binding sequence. CD6 binding to its ligand, CD166 (ALCAM), serves as a costimulatory molecule through its interaction with SLP-76. CD6 mediated signaling may contribute to thymocyte survival and functional avidity in mice and men.