CD79b anticorps

N° du produit ABIN2664824

Cet anticorps anti-CD79b Monoclonal Hamster arménien (Clone HM79-12) (ABIN2664824) détecte spécifiquement CD79b dans FACS. L’anticorps est réactif avec des échantillons de Souris.

Aperçu rapide pour CD79b anticorps (ABIN2664824)

Antigène: CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))

Reactivité: Souris

Hôte: Hamster arménien

Clonalité: Monoclonal

Conjugué: Cet anticorp CD79b est non-conjugé

Application: Flow Cytometry (FACS)

Clone: HM79-12

Détail du produit anti-CD79b anticorps

Purification: The antibody was purified by affinity chromatography.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur CD79b

Antigène: CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))

Autre désignation: CD79b

Sujet: Mouse CD79b (Igβ chain) is a 35-40kD transmembrane protein that forms a heterodimer with CD79a (30-35 kD, Ig α chain).The CD79b and CD79a hererodimers are associated with surface IgM to form the B-cell receptor (BCR) that is necessary for signal transduction via the BCR in mature B cells.CD79b participates signal transduction involved in the development of B cells as well. It was reported that association between CD79b/CD79a with IgM is essential in inducing both the transition from progenitor to precursor B cells and subsequent allelic exclusion.Igβ knockout mice had a complete block in B cell development at the immature CD43+B220+ stage. The HM79b-12 react with an extracellular epitope of CD79b or Ig β.

Pathways: BCR Signaling