CX3CR1 anticorps

N° du produit ABIN2664897

Détail du produit anti-CX3CR1 anticorps

Antigène: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Reactivité: Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CX3CR1 est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC)

Purification: The antibody was purified by affinity chromatography.

Clone: SA011F11

Isotype: IgG2a kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur CX3CR1

Antigène: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Autre désignation: CX3CR1 (CX3CR1 Produits)

Synonymes: anticorps CCRL1, anticorps CMKBRL1, anticorps CMKDR1, anticorps GPR13, anticorps GPRV28, anticorps V28, anticorps Rbs11, anticorps C-X3-C motif chemokine receptor 1, anticorps chemokine (C-X3-C motif) receptor 1, anticorps CX3C chemokine receptor 1, anticorps CX3CR1, anticorps Cx3cr1, anticorps LOC100559882

Sujet: CX3CR1 is a 40 kD, G-protein coupled receptor, with seven transmembrane regions. CX3CR1 is expressed by resident and alternatively activated macrophages (M2), a subset of monocytes, dendritic cells (DCs), NK cells, a subset of memory T cells, and mast cells. CX3CR1 is involved in cell recruitment during inflammation and participates in cell adhesion and extravasation from blood vessels. Its ligand is CX3CL1, also known as fractalkine or neurotactin. CX3CR1 is also a coreceptor for HIV1 and variations in this gene leads to increased susceptibility to HIV. In the brain, it is expressed by glial cells, which interact with CX3CL1 expressed by neurons.

Pathways: Cellular Response to Molecule of Bacterial Origin