CXCL16 anticorps

N° du produit ABIN2664903

Détail du produit anti-CXCL16 anticorps

Antigène: CXCL16 (Chemokine (C-X-C Motif) Ligand 16 (CXCL16))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CXCL16 est non-conjugé

Application: Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)

Purification: The antibody was purified by affinity chromatography.

Clone: 22-19-12

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur CXCL16

Antigène: CXCL16 (Chemokine (C-X-C Motif) Ligand 16 (CXCL16))

Autre désignation: CXCL16 (CXCL16 Produits)

Synonymes: anticorps CXCL16, anticorps 0910001K24Rik, anticorps AV290116, anticorps BB024863, anticorps CXCL16v1, anticorps CXCL16v2, anticorps SR-PSOX, anticorps Zmynd15, anticorps b2b498Clo, anticorps CXCLG16, anticorps SRPSOX, anticorps C-X-C motif chemokine ligand 16, anticorps chemokine (C-X-C motif) ligand 16, anticorps CXCL16, anticorps Cxcl16

Sujet: CXCL16, a 27 kD chemokine, exists in membrane-bound and soluble forms. Unlike classic chemokines, CXCL16 possesses a mucin-like stalk, a transmembrane domain, and a cytoplasmic tail with a tyrosine phosphorylation domain, allowing it to be expressed on the cell surface. Structurally, it is similar to fractalkine. It is expressed by dendritic cells, monocytes, and T cells. T cells can also migrate in response to CXCL16. CXCL16 can also act as a scavenger receptor on macrophages. Its receptor is CXCR6/Bonzo. It can bind oxidized LDL and thus may play an important role in atherosclerosis. Recent studies have shown a role for CXCL16 in kidney fibrosis and in autoimmunity. CXCL16 is also a co-receptor for HIV.