DDX6 anticorps
Aperçu rapide pour DDX6 anticorps (ABIN2664929)
Antigène
Voir toutes DDX6 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Purification
- The antibody was purified by affinity chromatography.
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Isotype
- IgG2a kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- DDX6 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 6 (DDX6))
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Autre désignation
- DDX6
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Sujet
- DDX6, also known as p54/RCK, is a member of the DEAD (Asp-Glu-Ala-Asp)-box RNA helicase family. DDX6 has been shown to localize to, and is required for the assembly of, processing bodies (P-bodies), which are cytoplasmic foci that consist of proteins involved in mRNA storage, processing, and turnover. DDX6 has ATP hydrolysis and RNA helicase activities, which are involved in secondary structure modulation and the degradation of mRNA. Interacting with key components of miRNA-induced silencing complexes, DDX6 participates in translational repression, as well. DDX6 is overexpressed in some colorectal tumor cells and can act as a proto-oncogene.
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Pathways
- Ribonucleoprotein Complex Subunit Organization
Antigène
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