IB-alpha anticorps

N° du produit ABIN2665062

Cet anticorps Souris Monoclonal détecte spécifiquement IB-alpha dans FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour IB-alpha anticorps (ABIN2665062)

Antigène: IB-alpha

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Application: Flow Cytometry (FACS)

Clone: 3D6C02

Détail du produit

Réactivité croisée: Souris

Réactivité croisée (Details): Weakly reacts with mouse

Purification: The antibody was purified by affinity chromatography.

Isotype: IgG2b kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détail du antigène

Antigène: IB-alpha

Sujet: IκB-α is an inhibitory protein that binds to the NF-κB complex and retains this complex in the cytoplasm where it cannot activate transcription. Upon cellular stimulation, the IκB proteins are phosphorylated and degraded via the ubiquitin pathway allowing for nuclear translocation of NF-κB. The NF-κB complex can then bind DNA to activate gene expression of multiple proteins involved in inflammation, cellular proliferation, differentiation, and apoptosis.