IL16 anticorps (AA 615-630)

N° du produit ABIN2665114

Détail du produit anti-IL16 anticorps

Antigène: IL16 (Interleukin 16 (IL16))

Épitope: AA 615-630

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IL16 est non-conjugé

Application: Flow Cytometry (FACS)

Réactivité croisée: Souris

Purification: The antibody was purified by affinity chromatography.

Immunogène: AA 615-630 (RRKSLQSKETTAAGDS) of IL-16

Clone: 14-1

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur IL16

Antigène: IL16 (Interleukin 16 (IL16))

Autre désignation: IL-16 (IL16 Produits)

Synonymes: anticorps IL16, anticorps LCF, anticorps NIL16, anticorps PRIL16, anticorps prIL-16, anticorps mKIAA4048, anticorps IL-16, anticorps interleukin 16, anticorps IL16, anticorps Il16

Sujet: Interleukin-16 is a proinflammatory cytokine synthesized as a 68 kD precursor molecule (pro-IL-16). After cleavage of pro-IL-16 by caspase-3, IL-16 is released as a 12 kD protein, but its biologic activities are exerted by a tetramer. IL-16 is a chemoattractant for CD4+ T cells, monocytes, and eosinophils. On T cells, IL-16 upregulates CD25 and class II expression, and also inhibits HIV-1 replication in vitro by repressing the transcription of the HIV-1 long terminal repeat. IL-16 is expressed by lymphocytes, macrophages, eosinophils, mast cells, epithelial cells, and fibroblasts. CD4 and CD9 are the receptors of IL-16.