IL-31 anticorps

N° du produit ABIN2665157

Détail du produit anti-IL-31 anticorps

Antigène: IL-31 (IL31) (Interleukin 31 (IL31))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp IL-31 est non-conjugé

Application: Biochemical Assay (BCA)

Purification: The antibody was purified by affinity chromatography.

Clone: 1C2B07

Isotype: IgG2b kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur IL-31

Antigène: IL-31 (IL31) (Interleukin 31 (IL31))

Autre désignation: IL-31 (IL31 Produits)

Synonymes: anticorps IL-31, anticorps 1700013B14Rik, anticorps IL31, anticorps interleukin 31, anticorps IL31, anticorps Il31

Sujet: IL-31, mainly produced by activated CD4+ T cells, is a helical cytokine belonging to the gp130/IL-6 cytokine family. IL-31 is closely related in structure to IL-6, IL-11, and IL-27. Binding of IL-31 to its receptor activates JAK/STAT, PI3K/AKT, and MAPK pathways. IL-31 acts on a broad range of immune and non-immune cells and thus possesses potential pleiotropic physiological functions, such as regulating hematopoiesis and immune response. Transgenic mice overexpressing IL-31 developed severe dermatitis, indicating that IL-31 is involved in skin immunity.