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IL33RA anticorps

Cet anticorps anti-IL33RA est un anticorps Rat Monoclonal détectant IL33RA dans IHC, FACS, BR et CyTOF. Adapté pour Souris.
N° du produit ABIN2665163

Aperçu rapide pour IL33RA anticorps (ABIN2665163)

Antigène

IL33RA (Interleukin 33 Receptor alpha (IL33RA))

Reactivité

Souris

Hôte

  • 3
Rat

Clonalité

  • 3
Monoclonal

Conjugué

  • 1
  • 1
  • 1
Cet anticorp IL33RA est non-conjugé

Application

  • 1
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (IHC), Flow Cytometry (FACS), Blocking Reagent (BR), Cytometry by Time of Flight (CyTOF)

Clone

DIH9
  • Purification

    The antibody was purified by affinity chromatography.

    Isotype

    IgG2a kappa
  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Concentration

    0.5 mg/mL

    Buffer

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C

    Stockage commentaire

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Antigène

    IL33RA (Interleukin 33 Receptor alpha (IL33RA))

    Autre désignation

    IL-33R alpha

    Sujet

    IL-33Rα, also known as ST2 or IL-1RL1, is a member of the Toll/IL-1 receptor family. It binds IL-33 and is structurally similar to IL-1R1. Two forms of the protein exist - a soluble form known as ST2 and a membrane anchored form known as ST2L. The membrane form is expressed by Th2 cells and bone marrow derived mast cells, whereas the soluble form is expressed by serum-stimulated fibroblasts. Blocking with anti-ST2 antibodies has been shown to alleviate experimental arthritis and airway inflammation. The IL-33-ST2 axis has been reported to be important across a range of diseases including asthma, allergies, and cardiac disease.
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