Pro-Major Basic Protein 1 anticorps

N° du produit ABIN2665341

Cet anticorps Souris Monoclonal détecte spécifiquement Pro-Major Basic Protein 1 dans FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Pro-Major Basic Protein 1 anticorps (ABIN2665341)

Antigène: Pro-Major Basic Protein 1

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Application: Flow Cytometry (FACS)

Clone: J175-7D4

Détail du produit

Purification: The antibody was purified by affinity chromatography.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détail du antigène

Antigène: Pro-Major Basic Protein 1

Sujet: Pro-form of Major Basic Protein 1 (ProMBP1) is composed of a strongly acidic 90-residue propart and a highly basic mature portion of 117 residues. It is an extensively and very heterogeneously glycosylated proteoglycan. ProMBP1 is processed to 14 kD MBP1 by convertase during maturation and localized in cell granule core. The mature MBP1 is a cytotoxic protein. The mAb J175-7D4 binds ProMBP1 and intermediate ProMBP1, but not mature MBP1. It specifically stain basophils, does not stain eosinophils, granulocytes, and mast cells and can be used as a marker for human basophils.