SYK anticorps

N° du produit ABIN2665378

L’anticorps anti-SYK Monoclonal Souris est utilisé pour la détection de SYK dans des échantillons de Humain. Il a été validé pour FACS et CyTOF.

Aperçu rapide pour SYK anticorps (ABIN2665378)

Antigène: SYK (Spleen tyrosine Kinase (SYK))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SYK est non-conjugé

Application: Flow Cytometry (FACS), Cytometry by Time of Flight (CyTOF)

Clone: 4D10-2

Détail du produit anti-SYK anticorps

Purification: The antibody was purified by affinity chromatography.

Isotype: IgG2a kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur SYK

Antigène: SYK (Spleen tyrosine Kinase (SYK))

Autre désignation: Syk

Sujet: Syk is a cytoplasmic 72 kD non-receptor tyrosine kinase that is widely expressed in hematopoietic cells. The Syk kinase associates with a number of proteins including c-Src, Lck, Lyn, Fyn, Vav1, STAT3, SHP1, Grb2, and LAT to couple immunoreceptors to downstream signaling events mediating cellular proliferation, differentiation, and phagocytosis. Syk is modified by phosphorylation on multiple tyrosine sites

Pathways: Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Thromboxane A2 Receptor Signaling, BCR Signaling