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IL-33 anticorps (AA 112-270)
IL33
Reactivité: Humain
IHC, FACS
Hôte: Chèvre
Polyclonal
Poly5163
unconjugated
N° du produit ABIN2665497
Détail du produit anti-IL-33 anticorps
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Antigène
Voir toutes IL-33 (IL33) Anticorps
IL-33 (IL33)
(Interleukin 33 (IL33))
Épitope
Tous les épitopes à travers IL-33 Anticorps.
AA 112-270
Reactivité
Toutes les réactivités sur IL-33 Anticorps
Humain
Hôte
Toutes les hôtes sur IL-33 Anticorps
Chèvre
Clonalité
Toutes les clonalités sur IL-33 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers IL-33 Anticorps
Cet anticorp IL-33 est non-conjugé
Application
Tous les applications à travers IL-33 Anticorps.
Immunohistochemistry (IHC), Flow Cytometry (FACS)
Réactivité croisée (Details)
In sandwich ELISA, no cross-reactivity with mouse or rat IL-33.
Purification
The antibody was purified by antigen affinity chromatography.
Immunogène
AA 112-270 (Accession# NM_033439) was expressed in E. coli.
Clone
Poly5163
Isotype
Ig Fraction, IgG
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Do not freeze.
Stock
4 °C
Stockage commentaire
The antibody solution should be stored undiluted between 2°C and 8°C.
Détails sur IL-33
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Antigène
IL-33 (IL33)
(Interleukin 33 (IL33))
Autre désignation
IL-33 (IL33 Produits )
Synonymes
anticorps IL33, anticorps C9orf26, anticorps DVS27, anticorps IL1F11, anticorps NF-HEV, anticorps NFEHEV, anticorps RP11-575C20.2, anticorps 9230117N10Rik, anticorps Il-33, anticorps Il1f11, anticorps RGD1311155, anticorps interleukin 33, anticorps IL33, anticorps Il33
Sujet
IL-33, also known as NFHEV and DVS 27, is a 30 kD proinflammatory protein that belongs to IL-1 superfamily. IL-33 is constitutively expressed in smooth muscle and airway epithelia. It is upregulated in arterial smooth muscle, dermal fibroblasts, and keratinocytes following IL-1α or IL-1β stimulation. IL-33 interacts with IL1RL1/ST2 receptor and IL-1 receptor accessory protein (IL1RAP) in order to activate intracellular molecules in the NF-κB and MAP kinase signaling pathways that drive production of type 2 cytokines (e.g. IL-5 and IL-13) from polarized Th2 cells. Recombinant IL-33 has been shown to enhance Th2-associated immune responses and potently increase mast cell proliferation and cytokine production.
Pathways
Production of Molecular Mediator of Immune Response
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