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IL-33 anticorps (Ser109)

IL33 Reactivité: Souris, Rat WB, IHC, IP, IF Hôte: Chèvre Polyclonal Poly5165 unconjugated
N° du produit ABIN2665498
  • Antigène Voir toutes IL-33 (IL33) Anticorps
    IL-33 (IL33) (Interleukin 33 (IL33))
    Épitope
    • 20
    • 16
    • 10
    • 9
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Ser109
    Reactivité
    • 83
    • 47
    • 38
    • 9
    • 1
    Souris, Rat
    Hôte
    • 103
    • 26
    • 7
    • 3
    • 2
    • 1
    • 1
    Chèvre
    Clonalité
    • 114
    • 29
    Polyclonal
    Conjugué
    • 71
    • 23
    • 13
    • 7
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp IL-33 est non-conjugé
    Application
    • 84
    • 68
    • 36
    • 28
    • 18
    • 15
    • 14
    • 14
    • 11
    • 10
    • 9
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)
     Réactivité croisée
    Rat (Rattus)
    Purification
    The antibody was purified by antigen affinity chromatography.
    Immunogène
    Ser109-Isoleucin266 (Accession# NM_133775) was expressed in E. coli.
    Clone
    Poly5165
    Isotype
    Ig Fraction, IgG
    Top Product
    Discover our top product IL33 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Do not freeze.
    Stock
    4 °C
    Stockage commentaire
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Antigène
    IL-33 (IL33) (Interleukin 33 (IL33))
    Autre désignation
    IL-33 (IL33 Produits)
    Synonymes
    anticorps IL33, anticorps C9orf26, anticorps DVS27, anticorps IL1F11, anticorps NF-HEV, anticorps NFEHEV, anticorps RP11-575C20.2, anticorps 9230117N10Rik, anticorps Il-33, anticorps Il1f11, anticorps RGD1311155, anticorps interleukin 33, anticorps IL33, anticorps Il33
    Sujet
    IL-33 belongs to the IL-1 family and is closely related in structure to IL-18 and IL-1b. IL-33, IL-1b, and IL-18 are synthesized as biologically inactive precursor and are cleaved by the enzyme caspase-1 to be secreted as active mature forms. IL-33 stimulates target cells by binding to the IL-1R/TLR superfamily member ST2 and subsequently activates NF-κB and MAPK pathways via identical signalling events to those observed for IL-1b. In addition, IL-33 is a nuclear factor (NF-HEV) abundantly expressed in high endothelial venules from lymphoid organs that associates with chromatin and exhibits transcriptional regulatory properties.
    Pathways
    Production of Molecular Mediator of Immune Response
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