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IL-33 anticorps (Ser109)
IL33
Reactivité: Souris, Rat
WB, IHC, IP, IF
Hôte: Chèvre
Polyclonal
Poly5165
unconjugated
N° du produit ABIN2665498
Détail du produit anti-IL-33 anticorps
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Antigène
Voir toutes IL-33 (IL33) Anticorps
IL-33 (IL33)
(Interleukin 33 (IL33))
Épitope
Tous les épitopes à travers IL-33 Anticorps.
Ser109
Reactivité
Toutes les réactivités sur IL-33 Anticorps
Souris, Rat
Hôte
Toutes les hôtes sur IL-33 Anticorps
Chèvre
Clonalité
Toutes les clonalités sur IL-33 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers IL-33 Anticorps
Cet anticorp IL-33 est non-conjugé
Application
Tous les applications à travers IL-33 Anticorps.
Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)
Réactivité croisée
Rat (Rattus)
Purification
The antibody was purified by antigen affinity chromatography.
Immunogène
Ser109-Isoleucin266 (Accession# NM_133775) was expressed in E. coli.
Clone
Poly5165
Isotype
Ig Fraction, IgG
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Do not freeze.
Stock
4 °C
Stockage commentaire
The antibody solution should be stored undiluted between 2°C and 8°C.
Détails sur IL-33
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Antigène
IL-33 (IL33)
(Interleukin 33 (IL33))
Autre désignation
IL-33 (IL33 Produits )
Synonymes
anticorps IL33, anticorps C9orf26, anticorps DVS27, anticorps IL1F11, anticorps NF-HEV, anticorps NFEHEV, anticorps RP11-575C20.2, anticorps 9230117N10Rik, anticorps Il-33, anticorps Il1f11, anticorps RGD1311155, anticorps interleukin 33, anticorps IL33, anticorps Il33
Sujet
IL-33 belongs to the IL-1 family and is closely related in structure to IL-18 and IL-1b. IL-33, IL-1b, and IL-18 are synthesized as biologically inactive precursor and are cleaved by the enzyme caspase-1 to be secreted as active mature forms. IL-33 stimulates target cells by binding to the IL-1R/TLR superfamily member ST2 and subsequently activates NF-κB and MAPK pathways via identical signalling events to those observed for IL-1b. In addition, IL-33 is a nuclear factor (NF-HEV) abundantly expressed in high endothelial venules from lymphoid organs that associates with chromatin and exhibits transcriptional regulatory properties.
Pathways
Production of Molecular Mediator of Immune Response
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