CD300a anticorps
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- Antigène Voir toutes CD300a (CD300A) Anticorps
- CD300a (CD300A)
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Reactivité
- Souris
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Hôte
- Rat
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD300a est non-conjugé
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Application
- Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Marque
- Ultra-LEAF™
- Purification
- The Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
- Stérilité
- 0.2 μm filtered
- niveau d'endotoxine
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Endotoxin level is <0.01 EU/μg of the protein (<0.001 ng/μg of the protein) as determined by the LAL test.
- Clone
- TX41
- Isotype
- IgG2a kappa
- Top Product
- Discover our top product CD300A Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Agent conservateur
- Azide free
- Conseil sur la manipulation
- This Ultra-LEAF™ solution contains no preservative, handle under aseptic conditions
- Stock
- 4 °C
- Stockage commentaire
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Antigène
- CD300a (CD300A)
- Autre désignation
- CD300a (CD300A Produits)
- Synonymes
- anticorps CD300L-B1, anticorps CD300A, anticorps clm8, anticorps B230315M08Rik, anticorps Clm8, anticorps LMIR1, anticorps MAIR-I, anticorps MAIR-Ia, anticorps MMAC8, anticorps Pigr4, anticorps mcpir1, anticorps CLM-8, anticorps CMRF-35-H9, anticorps CMRF-35H, anticorps CMRF35-H, anticorps CMRF35-H9, anticorps CMRF35H, anticorps CMRF35H9, anticorps IGSF12, anticorps IRC1, anticorps IRC1/IRC2, anticorps IRC2, anticorps IRp60, anticorps CD300 molecule like family member g, anticorps CD300a molecule, anticorps CMRF35-like molecule 8, anticorps CD300A molecule, anticorps Cd300a molecule, anticorps CD300LG, anticorps CD300A, anticorps LOC483289, anticorps clm8, anticorps Cd300a
- Sujet
- CD300 receptors are a group of type I transmembrane proteins, which belong to the Ig superfamily. In mice, nine members have been reported with different nomenclature systems, such as myeloid-associated Ig-like receptor (MAIR), leukocyte mono-Ig-like receptor (LMIR), DC-derived Ig-like receptor (DIgR), and CMRF-35-like molecule (CLM). The CD300 Molecules act as either activating or inhibitory receptors through interactions with adaptor molecules, such as PAD12, DAP10, and FcRγ. CD300a is an inhibitory receptor that is mainly expressed on peripheral eosinophils, mast cells, neutrophils, dendritic cells, macrophages, and some B cells. Cross-linking CD300a by an antibody can induce phosphorylation of tyrosine residues in the cytoplasmic domain, which results in recruitment of phosphatases SHIP, SHP1 and SHP2 and inhibition of cell activation.
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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