Leucine Peptidase anticorps

N° du produit ABIN2666017

Détail du produit

Antigène: Leucine Peptidase

Reactivité: Souris, Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC)

Marque: Ultra-LEAF™

Purification: The Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.

Stérilité: 0.2 μm filtered

niveau d'endotoxine:

Endotoxin level is <0.01 EU/μg of the protein (<0.001 ng/μg of the protein) as determined by the LAL test.

Clone: TW7-28G11

Isotype: IgG2b kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Agent conservateur: Azide free

Conseil sur la manipulation: This Ultra-LEAF™ solution contains no preservative, handle under aseptic conditions

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détail du antigène

Antigène: Leucine Peptidase

Autre désignation: LAP

Sujet: Transforming growth factor beta (TGF-β) is a cytokine that has critical functions in the immune response by regulating Treg and Th17 cell differentiation. TGF-β is first synthesized as pro-TGF-β which is then cleaved by furin proprotein convertase in the Golgi apparatus to produce a latent TGF-β complex. This complex consists of non-covalently associated dimers of the N-terminal region of pro-TGF-β (latency-associated peptide, LAP) and C-terminal region of pro-TGF-β (mature TGF-β). The latent-TGF-β has been found on the membrane of activated Treg cells, immature dendritic cells, megakaryocytes, and platelets.