Leucine Peptidase anticorps
Aperçu rapide pour Leucine Peptidase anticorps (ABIN2666017)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Attributs du produit
- This product is produced with low endotoxin and is supplied azide free.
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Purification
- The Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
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Stérilité
- 0.2 μm filtered
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niveau d'endotoxine
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Endotoxin level is <0.01 EU/μg of the protein (<0.001 ng/μg of the protein) as determined by the LAL test.
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Isotype
- IgG2b kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Agent conservateur
- Azide free
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Conseil sur la manipulation
- This Ultra-LEAF™ solution contains no preservative, handle under aseptic conditions
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Stock
- 4 °C
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Stockage commentaire
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Leucine Peptidase
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Autre désignation
- LAP
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Sujet
- Transforming growth factor beta (TGF-β) is a cytokine that has critical functions in the immune response by regulating Treg and Th17 cell differentiation. TGF-β is first synthesized as pro-TGF-β which is then cleaved by furin proprotein convertase in the Golgi apparatus to produce a latent TGF-β complex. This complex consists of non-covalently associated dimers of the N-terminal region of pro-TGF-β (latency-associated peptide, LAP) and C-terminal region of pro-TGF-β (mature TGF-β). The latent-TGF-β has been found on the membrane of activated Treg cells, immature dendritic cells, megakaryocytes, and platelets.
Antigène
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