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IRF1 anticorps

IRF1 Reactivité: Humain WB Hôte: Souris Monoclonal 13H3A44 unconjugated
N° du produit ABIN2666257
  • Antigène Voir toutes IRF1 Anticorps
    IRF1 (Interferon Regulatory Factor 1 (IRF1))
    Reactivité
    • 88
    • 48
    • 34
    • 9
    • 9
    • 8
    • 8
    • 7
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 92
    • 6
    • 1
    • 1
    Souris
    Clonalité
    • 84
    • 16
    Monoclonal
    Conjugué
    • 49
    • 12
    • 9
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp IRF1 est non-conjugé
    Application
    • 88
    • 33
    • 14
    • 12
    • 11
    • 8
    • 7
    • 6
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Purification
    Affinity purified.
    Clone
    13H3A44
    Isotype
    IgG2a kappa
    Top Product
    Discover our top product IRF1 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Upon receipt, store undiluted at 4°C.
  • Antigène
    IRF1 (Interferon Regulatory Factor 1 (IRF1))
    Autre désignation
    IRF1 (IRF1 Produits)
    Synonymes
    anticorps irf1, anticorps zgc:136945, anticorps IRF1, anticorps irf11, anticorps zgc:103566, anticorps IRF-1, anticorps MAR, anticorps AU020929, anticorps Irf-1, anticorps interferon regulatory factor 1, anticorps interferon regulatory factor 1a, anticorps interferon regulatory factor 1b, anticorps IRF1, anticorps irf1a, anticorps irf1b, anticorps Irf1
    Sujet
    IRF1 is the first identified member of the interferon regulatory transcription factor family. Its expression is induced in response to pathogen infection or the stimulation of several cytokines, including type I and II IFN, IL-1, IL-6, and TNF-α. Upon stimulation, IRF1 is transcriptionally activated by STAT1 and NFκB transcription factors via the GAS (interferon-gamma-activated sequence) element in the IRF1 promoter. IRF1 plays important roles in mediating immune response during infection and development of T cells and NK cells. In addition to the immunomodulatory functions, IRF1 has also shown to be involved in the regulation of cell cycle progression, tumor suppression, and apoptosis. IRF1-mediated transcription can be repressed by IRF2 through competing for the same binding region on the promoters.
    Pathways
    Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Immune Effector Process, Hepatitis C, Autophagy
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