c-Rel anticorps

N° du produit ABIN2666277

Cet anticorps Souris Monoclonal détecte spécifiquement c-Rel dans FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour c-Rel anticorps (ABIN2666277)

Antigène: c-Rel (REL proto-oncogene (c-Rel))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp c-Rel est non-conjugé

Application: Flow Cytometry (FACS)

Clone: 2F5A22

Détail du produit anti-c-Rel anticorps

Purification: Affinity purified

Isotype: IgG2b kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Upon receipt, store undiluted between 2°C and 8°C.

Détails sur c-Rel

Antigène: c-Rel (REL proto-oncogene (c-Rel))

Autre désignation: C-REL

Sujet: C-Rel is a member of the Rel/NF-κB transcription factor family that forms homo or heterodimers with family members such as RelA/p65, RelB, NF- κB1/p105, and NF-κB2/p100. The NF-κB complex is retained in cytoplasm by the inhibitor IκB protein in unstimulated cells. Upon activation, IκB is degraded via the ubiquitin-proteasome pathway, which results in nuclear translocation of the active NF-κB complex. While other NF-κB transcription factors are expressed in most cell types, relatively higher levels of c-REL expression are found in hematopoietic cells. c-REL is thought to play key roles in regulating proliferation, differentiation, and survival of B and T lymphocytes.