RAG2 anticorps
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- Antigène Voir toutes RAG2 Anticorps
- RAG2 (Recombination Activating Gene 2 (RAG2))
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Reactivité
- Humain, Souris
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp RAG2 est non-conjugé
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Application
- Western Blotting (WB)
- Purification
- Affinity purified.
- Clone
- 3G4A26
- Isotype
- IgG2b kappa
- Top Product
- Discover our top product RAG2 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- phosphate-buffered solution, pH 7.2, containing 0.05 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- Upon receipt, store undiluted between 2°C and 8°C.
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- Antigène
- RAG2 (Recombination Activating Gene 2 (RAG2))
- Autre désignation
- RAG2 (RAG2 Produits)
- Synonymes
- anticorps RAG-2, anticorps Rag-2, anticorps rag-2, anticorps zgc:136743, anticorps recombination activating 2, anticorps recombination activating gene 2, anticorps recombination activating gene 2 S homeolog, anticorps RAG2, anticorps Rag2, anticorps rag2, anticorps rag2.S
- Sujet
- During T cell and B cell development, RAG2 works together with RAG1 to induce DNA rearrangement and assembly of antigen receptor coding segments. Defects in RAG2 gene lead to the complete lack of mature T and B lymphocytes and result in severe combined immunodeficiency (SCID). RAG2 also functions in chromosome binding through its unique plant homeodomain (PHD). Sequestration of recombination signal sequences (RSS) within the nucleosome by RAG2 prevents access by the recombinase complex.
- Pathways
- Chromatin Binding, Production of Molecular Mediator of Immune Response
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