BCL11B anticorps

N° du produit ABIN2666299

L’anticorps Rat Monoclonal anti-BCL11B a été validé pour FACS. Il convient pour détecter BCL11B dans des échantillons de Humain.

Aperçu rapide pour BCL11B anticorps (ABIN2666299)

Antigène: BCL11B (B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B))

Reactivité: Humain

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp BCL11B est non-conjugé

Application: Flow Cytometry (FACS)

Clone: 25B6

Détail du produit anti-BCL11B anticorps

Réactivité croisée: Souris, Poisson Zèbre

Réactivité croisée (Details): Mouse, Zebrafish

Purification: Protein G affinity purified.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Hepes-buffered solution, pH 7.5, 0.02 % Sodium azide .

Stock: 4 °C

Stockage commentaire: Upon receipt, store undiluted between 2°C and 8°C.

Détails sur BCL11B

Antigène: BCL11B (B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B))

Autre désignation: Bcl11b

Sujet: The transcription factor Bcl11b is expressed in thymus, mainly T cells. It is indispensable for T lineage development. When Bcl11b was deleted, T cells from all developmental stages acquired NK cell properties and concomitantly lost or decreased T cell-associated gene expression. These induced T-to-natural killer (ITNK) cells, which were morphologically and genetically similar to conventional NK cells, killed tumor cells in vitro, and effectively prevented tumor metastasis in vivo. Therefore, ITNKs may represent a new cell source for cell-based therapies.