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BCL11B anticorps

BCL11B Reactivité: Humain FACS Hôte: Rat Monoclonal 25B6 unconjugated
N° du produit ABIN2666299
  • Antigène Voir toutes BCL11B Anticorps
    BCL11B (B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B))
    Reactivité
    • 48
    • 9
    • 8
    • 7
    • 7
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    Humain
    Hôte
    • 48
    • 1
    • 1
    Rat
    Clonalité
    • 40
    • 10
    Monoclonal
    Conjugué
    • 28
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Cet anticorp BCL11B est non-conjugé
    Application
    • 29
    • 15
    • 12
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
     Réactivité croisée
    Souris, Poisson Zèbre
    Réactivité croisée (Details)
    Mouse, Zebrafish
    Purification
    Protein G affinity purified.
    Clone
    25B6
    Isotype
    IgG
    Top Product
    Discover our top product BCL11B Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    Hepes-buffered solution, pH 7.5, 0.02 % Sodium azide .
    Stock
    4 °C
    Stockage commentaire
    Upon receipt, store undiluted between 2°C and 8°C.
  • Antigène
    BCL11B (B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B))
    Autre désignation
    Bcl11b (BCL11B Produits)
    Synonymes
    anticorps BCL11B, anticorps 9130430L19Rik, anticorps AI604821, anticorps B630002E05Rik, anticorps BCL-11B, anticorps Ctip2, anticorps Rit1, anticorps ATL1, anticorps ATL1-alpha, anticorps ATL1-beta, anticorps ATL1-delta, anticorps ATL1-gamma, anticorps CTIP-2, anticorps CTIP2, anticorps RIT1, anticorps ZNF856B, anticorps hRIT1-alpha, anticorps B-cell CLL/lymphoma 11B, anticorps B cell leukemia/lymphoma 11B, anticorps B-cell CLL/lymphoma 11B (zinc finger protein), anticorps BCL11B, anticorps Bcl11b
    Sujet
    The transcription factor Bcl11b is expressed in thymus, mainly T cells. It is indispensable for T lineage development. When Bcl11b was deleted, T cells from all developmental stages acquired NK cell properties and concomitantly lost or decreased T cell-associated gene expression. These induced T-to-natural killer (ITNK) cells, which were morphologically and genetically similar to conventional NK cells, killed tumor cells in vitro, and effectively prevented tumor metastasis in vivo. Therefore, ITNKs may represent a new cell source for cell-based therapies.
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