LIN28A anticorps

N° du produit ABIN2666352

Cet anticorps Souris Monoclonal détecte spécifiquement LIN28A dans FACS et BR. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour LIN28A anticorps (ABIN2666352)

Antigène: LIN28A (Lin-28 Homolog A (C. Elegans) (LIN28A))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LIN28A est non-conjugé

Application: Flow Cytometry (FACS), Blocking Reagent (BR)

Clone: 14E6-4E6

Détail du produit anti-LIN28A anticorps

Purification: The antibody was purified by affinity chromatography.

Isotype: IgG2a, IgG2a kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Upon receipt, store undiluted between 2°C and 8°C.

Détails sur LIN28A

Antigène: LIN28A (Lin-28 Homolog A (C. Elegans) (LIN28A))

Autre désignation: Lin28A

Sujet: LIN28A is a highly conserved RNA-binding protein and reprogramming factor that plays important roles in development, self-renewal of stem cells, glucose metabolism and tumorigenesis. Lin28A modulates not only miRNAs, particularly the let-7 family miRNAs, but also the translation of mRNAs that are important for cell growth and metabolism. LIN28A/B has been observed to be overexpressed in a wide range of solid tumors and hematological malignancies, and has emerged as a new therapeutic target candidate for cancer.

Pathways: Stem Cell Maintenance