SSRP1 anticorps
Aperçu rapide pour SSRP1 anticorps (ABIN2666368)
Antigène
Voir toutes SSRP1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Purification
- The antibody was purified by affinity chromatography.
-
Isotype
- IgG2b kappa
-
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Concentration
- 0.5 mg/mL
-
Buffer
- phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide at 0.5 mg/mL.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- 4 °C
-
Stockage commentaire
- Upon receipt, store undiluted between 2°C and 8°C.
-
-
- SSRP1 (Structure Specific Recognition Protein 1 (SSRP1))
-
Autre désignation
- SSRP1
-
Sujet
- SSRP1 is a nuclear protein and a component of the FACT complex (facilitates chromatin transcription). The FACT complex is composed of the SUPT16H (FACT140) and the SSRP1 FACTp80 proteins. This complex interacts with nucleosomes and histone H2A/H2B dimers to promote nucleosome disassembly and allow transcription elongation. This protein interacts with dsDNA. The SSRP1 protein has been shown to be modified by cisplatin and may protect DNA from repair and block DNA replication. The 10D1 monoclonal antibody recognizes the human SSRP1 protein and has been shown to be useful for Western blotting.
-
Pathways
- Chromatin Binding
Antigène
-