Histone H2A anticorps (H2AS129ph)

N° du produit ABIN2668303

Il existe 1 publication pour ce produit. L’anticorps anti-Histone H2A Polyclonal Lapin est utilisé pour la détection de Histone H2A dans des échantillons de Saccharomyces cerevisiae. Il a été validé pour WB, DB et ChIP.

Aperçu rapide pour Histone H2A anticorps (H2AS129ph) (ABIN2668303)

Antigène: Histone H2A

Reactivité: Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Histone H2A est non-conjugé

Application: Western Blotting (WB), Dot Blot (DB), Chromatin Immunoprecipitation (ChIP)

Détail du produit anti-Histone H2A anticorps

Épitope: H2AS129ph

Fonction: Histone H2AS129ph antibody (pAb)

Purification: Unpurified

Immunogène: This Histone H2A phospho Ser129 antibody was raised against a peptide including phospho-serine 129 of budding yeast Histone H2A.

Information d'application

Indications d'application: WB: 1:500 - 1:2,000 dilution

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit serum containing 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Stock: -20 °C

Stockage commentaire: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Date de péremption: 24 months

Références pour anticorps anti-Histone H2A (ABIN2668303)

Jha, Strahl: "An RNA polymerase II-coupled function for histone H3K36 methylation in checkpoint activation and DSB repair." dans: Nature communications, Vol. 5, pp. 3965, (2014) (PubMed).

Détails sur Histone H2A

Antigène: Histone H2A

Sujet: Histone H2A is one of the core components of the nucleosome, the basic building block of chromatin. Unlike mammals that have a distinct DNA damage-responsive histone H2A variant, H2AX, budding yeast histone H2A contains an SQ motif in the C-terminus that is phosphorylated by the Mec1 and Tel1 kinases in response to DNA double strand breaks. As with mammalian H2AX phosphorylation, phosphorylation of yeast histone H2A at serine 129 is required for the efficient repair of DNA double-strand breaks.

Poids moléculaire: 14 kDa

NCBI Accession: NP_010511