PHC1 anticorps

N° du produit ABIN2668352

Cité dans 2 publications. Cet anticorps anti-PHC1 Monoclonal Souris (Clone 6-1-3) (ABIN2668352) détecte spécifiquement PHC1 dans WB, IF, IP et ICC. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour PHC1 anticorps (ABIN2668352)

Antigène: PHC1 (Polyhomeotic-Like 1 (PHC1))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PHC1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Clone: 6-1-3

Détail du produit anti-PHC1 anticorps

Fonction: Phc1 antibody (mAb) (Clone 6-1-3)

Purification: Protein G Chromatography

Immunogène: This Phc1 antibody was raised against a recombinant mouse Phc1 protein fragment.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1 μg/μL

Buffer: Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Stock: -20 °C

Stockage commentaire: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Date de péremption: 24 months

Références pour anticorps anti-PHC1 (ABIN2668352)

Lin, Shen, Li, Tang, Gu, Chen, Hu, Rice, Lu, Wu: "Proteomic and functional analyses reveal the role of chromatin reader SFMBT1 in regulating epigenetic silencing and the myogenic gene program." dans: The Journal of biological chemistry, Vol. 288, Issue 9, pp. 6238-47, (2013) (PubMed).

Miyagishima, Isono, Fujimura, Iyo, Takihara, Masumoto, Vidal, Koseki: "Dissociation of mammalian Polycomb-group proteins, Ring1B and Rae28/Ph1, from the chromatin correlates with configuration changes of the chromatin in mitotic and meiotic prophase." dans: Histochemistry and cell biology, Vol. 120, Issue 2, pp. 111-9, (2003) (PubMed).

Détails sur PHC1

Antigène: PHC1 (Polyhomeotic-Like 1 (PHC1))

Autre désignation: Phc1

Sujet: Phc1, polyhomeotic homolog 1 (also known as EDR1, early development regulatory protein 1) is a component of the polycomb group (PcG) multiprotein PRC1 complex. The PRC1 complex is required to maintain the stable repression of the Hox genes during development. This chromatin-associated protein complex acts via chromatin remodeling and histone modifications. Phc1 has been shown to interact with PHC2, BMI1, MAPKAPK2 and MCRS1.

Poids moléculaire: 150 kDa

ID gène: 1911

NCBI Accession: NP_001036088