SIN3A anticorps (N-Term)

N° du produit ABIN2668357

Il existe 1 publication pour ce produit. L’anticorps anti-SIN3A Polyclonal Lapin est utilisé pour la détection de SIN3A dans des échantillons de Humain et Souris. Il a été validé pour WB et ChIP.

Aperçu rapide pour SIN3A anticorps (N-Term) (ABIN2668357)

Antigène: SIN3A (SIN3 homolog A, transcription regulator (SIN3A))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIN3A est non-conjugé

Application: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)

Détail du produit anti-SIN3A anticorps

Épitope: N-Term

Fonction: SIN3A antibody (pAb)

Purification: Unpurified

Immunogène: This SIN3A antibody was raised against a peptide derived from the N-terminus of human SIN3A.

Information d'application

Indications d'application: ChIP: 5 - 10 µL per ChIP WB*: 1:1,000 - 1:5,000 dilution *Note: many chromatin-bound proteins are not soluble in a low salt nuclear extract and fractionate to the pellet. Therefore, we recommend a High Salt / Sonication Protocol when preparing nuclear extracts for Western Blot.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit serum containing 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Stock: -20 °C

Stockage commentaire: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Date de péremption: 24 months

Références pour anticorps anti-SIN3A (ABIN2668357)

Chalei, Sansom, Kong, Lee, Montiel, Vance, Ponting: "The long non-coding RNA Dali is an epigenetic regulator of neural differentiation." dans: eLife, Vol. 3, pp. e04530, (2014) (PubMed).

Détails sur SIN3A

Antigène: SIN3A (SIN3 homolog A, transcription regulator (SIN3A))

Autre désignation: SIN3A

Sujet: SIN3A (Switch independent 3 homologue) is the mammalian homologue of the yeast protein Sin3. SIN3A is transcriptional co-repressor that is recruited to promoters by sequence-specific DNA binding proteins, such as REST, MXI1 and MAD-MAX. It is part of a large multi-subunit repressor protein complex that also contains HDAC1, HDAC2 and SMRT/NCoR1.

Poids moléculaire: 155 kDa

ID gène: 25942

NCBI Accession: NP_001138829

Pathways: Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha