MAD2L1 anticorps

N° du produit ABIN2668530

Cet anticorps Souris Monoclonal détecte spécifiquement MAD2L1 dans WB. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour MAD2L1 anticorps (ABIN2668530)

Antigène: MAD2L1 (MAD2 Mitotic Arrest Deficient-Like 1 (Yeast) (MAD2L1))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MAD2L1 est non-conjugé

Application: Western Blotting (WB)

Clone: 17D10

Détail du produit anti-MAD2L1 anticorps

Fonction: MAD2L1 antibody (mAb) (Clone 17D10)

Purification: Protein G Chromatography

Immunogène: This MAD2L1 antibody was raised against full-length recombinant human MAD2L1.

Isotype: IgG1

Information d'application

Indications d'application: WB: 2 - 5 μg/mL dilution

Restrictions: For Research Use only

Stockage

Concentration: 1 μg/μL

Buffer: Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Stock: -20 °C

Stockage commentaire: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Date de péremption: 24 months

Détails sur MAD2L1

Antigène: MAD2L1 (MAD2 Mitotic Arrest Deficient-Like 1 (Yeast) (MAD2L1))

Autre désignation: MAD2L1

Sujet: MAD2L1 (aka HSMAD2, MAD2, MAD2-like 1) is the human homolog of the budding yeast MAD2, or mitotic arrest deficient 2 gene. MAD2L1 is a component of the mitotic spindle assembly checkpoint, which monitors the attachment of the mitotic spindle to the kinetochores of segregating chromosomes and delays the onset of anaphase until attachment is complete and the chromosomes are properly aligned on the metaphase plate. MAD2L1 associates only with unattached kinetochores in prometaphase, and prevents cell cycle progression by associating with the Anaphase Promoting Complex (APC), specifically restricting the activity of the CDC20 protein.

Poids moléculaire: 23 kDa

ID gène: 4085

NCBI Accession: NP_002349