CHD2 anticorps (C-Term)
Aperçu rapide pour CHD2 anticorps (C-Term) (ABIN2668552)
Antigène
Voir toutes CHD2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Fonction
- CHD2 antibody (pAb)
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Purification
- Affinity Purified
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Immunogène
- This CHD2 antibody (pAb) was raised against a peptide corresponding to the C-terminus of human CHD2.
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Isotype
- IgG
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Indications d'application
- WB: 1:250 - 1:1,000 dilution The addition of 0.1 % Tween 20 in all blocking solutions may reduce background. Individual optimization may be required.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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Stock
- -20 °C
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Stockage commentaire
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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Date de péremption
- 24 months
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- CHD2 (Chromodomain Helicase DNA Binding Protein 2 (CHD2))
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Autre désignation
- CHD2
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Sujet
- CHD (Chromo-ATPase/Helicase-DNA-binding) proteins, which are ATP-dependent chromatin remodeling factors implicated in RNA polymerase II transcriptional regulation, are characterized by the presence of a double chromodomains (Chromatin Organization Modifier) and SNF2-related helicase/ATPase domains. The CHD1/CHD2 sub-family of CHD proteins also contain a C-terminal DNA binding domain that recognizes AT-rich sequences. CHD proteins alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. CHD2 is required for normal development of mouse embryos.
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Poids moléculaire
- 260 kDa
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ID gène
- 1106
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NCBI Accession
- NP_001262
Antigène
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