Histone H1 anticorps

N° du produit ABIN2667975

Cet anticorps Lapin Polyclonal détecte spécifiquement Histone H1 dans WB, IF et ICC. Il présente une réactivité avec des échantillons de Humain. Il a été cité dans 2+ publications.

Aperçu rapide pour Histone H1 anticorps (ABIN2667975)

Antigène: Histone H1

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Histone H1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-Histone H1 anticorps

Fonction: Histone H1 antibody (pAb)

Purification: Unpurified

Immunogène: This Histone H1 antibody was raised against calf thymus histone H1.

Information d'application

Indications d'application: ICC/IF: 1:500 - 1:1,000 dilution WB: 1:500 - 1:5,000 dilution

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit serum containing 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Stock: -20 °C

Stockage commentaire: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Date de péremption: 24 months

Références pour anticorps anti-Histone H1 (ABIN2667975)

Li, Wu, Kim, Zhao, Hearn, Zhang, Meistrich, Mills: "Chd5 orchestrates chromatin remodelling during sperm development." dans: Nature communications, Vol. 5, pp. 3812, (2014) (PubMed).

Hagarman, Motley, Kristjansdottir, Soloway: "Coordinate regulation of DNA methylation and H3K27me3 in mouse embryonic stem cells." dans: PLoS ONE, Vol. 8, Issue 1, pp. e53880, (2013) (PubMed).

Détails sur Histone H1

Antigène: Histone H1

Sujet: The nucleosome is the smallest subunit of chromatin and consists of 147 base pairs of DNA wrapped around an octamer of core histone proteins (two each of Histone H2A, Histone H2B, Histone H3 and Histone H4). Histone H1 is a linker histone, present at the interface between the nucleosome core and DNA entry/exit points, it is responsible for establishing higher-order chromatin structure. Chromatin is subject to a variety of chemical modifications, including post-translational modifications of the histone proteins and the methylation of cytosine residues in the DNA. Reported histone modifications include acetylation, methylation, phosphorylation, ubiquitylation, glycosylation, ADP-ribosylation, carbonylation and SUMOylation, they play a major role in regulating gene expression.

Poids moléculaire: 31 kDa

ID gène: 3006

NCBI Accession: XP_010816821