SNAIL anticorps

N° du produit ABIN2668578

Cet anticorps Rat Monoclonal détecte spécifiquement SNAIL dans WB et IHC. Il présente une réactivité avec des échantillons de Humain. Il a été cité dans 2+ publications.

Aperçu rapide pour SNAIL anticorps (ABIN2668578)

Antigène: SNAIL (SNAI1)

Reactivité: Humain

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp SNAIL est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: 9H2

Détail du produit anti-SNAIL anticorps

Fonction: SNAI1 / Snail antibody (mAb) (Clone 9H2)

Purification: Protein G Chromatography

Immunogène: This antibody was raised against a full-length recombinant protein corresponding to human SNAI1.

Isotype: IgG2a

Information d'application

Indications d'application: This antibody is also available as an AbFlex engineered recombinant antibody. For details on the corresponding AbFlex Recombinant Antibody, see Catalog No. 91255.

Restrictions: For Research Use only

Stockage

Concentration: 1 μg/μL

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Stock: -20 °C

Stockage commentaire: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Date de péremption: 24 months

Références pour anticorps anti-SNAIL (ABIN2668578)

Yanagawa, Walser, Zhu, Hong, Fishbein, Mah, Chia, Goodglick, Elashoff, Luo, Magyar, Dohadwala, Lee, St John, Strieter, Sharma, Dubinett: "Snail promotes CXCR2 ligand-dependent tumor progression in non-small cell lung carcinoma." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 22, pp. 6820-9, (2009) (PubMed).

Rosivatz, Becker, Kremmer, Schott, Blechschmidt, Höfler, Sarbia: "Expression and nuclear localization of Snail, an E-cadherin repressor, in adenocarcinomas of the upper gastrointestinal tract." dans: Virchows Archiv : an international journal of pathology, Vol. 448, Issue 3, pp. 277-87, (2006) (PubMed).

Détails sur SNAIL

Antigène: SNAIL (SNAI1)

Autre désignation: SNAI1 / Snail

Sujet: SNAI1 / Snail (snail homolog 1 (Drosophila)) is involved in the epithelial to mesenchymal transition (EMT) and formation and maintenance of embryonic mesoderm (By similarity). Binds to 3 E-boxes of the E-cadherin gene promoter and represses its transcription.

Poids moléculaire: 32 kDa

ID gène: 6615

NCBI Accession: NP_005976

Pathways: Negative Regulation of intrinsic apoptotic Signaling