ASCL1 anticorps

N° du produit ABIN2668587

Cet anticorps Souris Monoclonal détecte spécifiquement ASCL1 dans WB et IHC. Il présente une réactivité avec des échantillons de Souris et Rat. Il a été cité dans 3+ publications.

Aperçu rapide pour ASCL1 anticorps (ABIN2668587)

Antigène: ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))

Reactivité: Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ASCL1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: 24B7-2D11-1

Détail du produit anti-ASCL1 anticorps

Fonction: MASH1 antibody (mAb) (Clone 24B7.2D11.1)

Purification: Protein A Chromatography

Immunogène: This MASH1 antibody was raised against a full-length protein corresponding to rat MASH1.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1 μg/μL

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Stock: -20 °C

Stockage commentaire: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Date de péremption: 24 months

Références pour anticorps anti-ASCL1 (ABIN2668587)

Ivaniutsin, Chen, Mason, Price, Pratt: "Adenomatous polyposis coli is required for early events in the normal growth and differentiation of the developing cerebral cortex." dans: Neural development, Vol. 4, Issue 1, pp. 3, (2009) (PubMed).

Ralston, Chiriboga, Nonaka: "MASH1: a useful marker in differentiating pulmonary small cell carcinoma from Merkel cell carcinoma." dans: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 21, Issue 11, pp. 1357-62, (2008) (PubMed).

Lo, Johnson, Wuenschell, Saito, Anderson: "Mammalian achaete-scute homolog 1 is transiently expressed by spatially restricted subsets of early neuroepithelial and neural crest cells." dans: Genes & development, Vol. 5, Issue 9, pp. 1524-37, (1991) (PubMed).

Détails sur ASCL1

Antigène: ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))

Autre désignation: MASH1

Sujet: The MASH1 (achaete-scute complex homolog 1 (Drosophila), ASCL1, ASH1, HASH1) gene encodes a protein that is a basic helix-loop-helix transcription factor that may play a role at early stages of development of specific neural lineages in most regions of the CNS, and of several lineages in the PNS. Essential for the generation of olfactory and autonomic neurons. Involved in the initiation of neuronal differentiation. Mediates transcriptional activation by binding to the E box motif.

Poids moléculaire: 34 kDa

ID gène: 64186

NCBI Accession: NP_071779

Pathways: Dopaminergic Neurogenesis