ESRRA anticorps (C-Term)

N° du produit ABIN2668679

Cet anticorps anti-ESRRA Polyclonal Lapin (ABIN2668679) détecte spécifiquement ESRRA dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour ESRRA anticorps (C-Term) (ABIN2668679)

Antigène: ESRRA (Estrogen-Related Receptor alpha (ESRRA))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ESRRA est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ESRRA anticorps

Épitope: C-Term

Fonction: ERR-a antibody (pAb)

Purification: Affinity Purified

Immunogène: This ERR-alpha antibody was raised against a peptide within the C-terminal region of human ERR alpha.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500 - 1:1,000 dilution

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Stock: -20 °C

Stockage commentaire: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Date de péremption: 24 months

Détails sur ESRRA

Antigène: ESRRA (Estrogen-Related Receptor alpha (ESRRA))

Autre désignation: ERR-alpha

Sujet: ERR-a (Estrogen-related receptor alpha, NR3B1) is an orphan nuclear receptor similar to the Estrogen Receptor. It is a sequence-specific DNA binding transcriptional activator that is constitutively active in the absence of ligand binding. No true physiological ligands have been found, but estrogen-like compounds from plants have been shown to activate ERR-a. ERR-a and ER-a have been found to regulate an overlapping set of genes, and ERR-a appears to modulate the activity of ER-a in some tissue types. ERR-a regulates genes involved in mitochondrial biogenesis, gluconeogenesis, oxidative phosphorylation, and fatty acid metabolism. ERR-a knockout mice display impaired fat metabolism and absorption.

Poids moléculaire: 50 kDa

ID gène: 2101

NCBI Accession: NP_004442

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha