Retinoid X Receptor gamma anticorps
Aperçu rapide pour Retinoid X Receptor gamma anticorps (ABIN2668700)
Antigène
Voir toutes Retinoid X Receptor gamma (RXRG) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- RXR-gamma antibody (mAb) (Clone 12RX-2D3)
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Purification
- Protein G Chromatography
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Immunogène
- This RXR-gamma antibody was raised against a peptide within the D-region of mouse RXR-gamma.
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1 μg/μL
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Buffer
- Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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Stock
- -20 °C
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Stockage commentaire
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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Date de péremption
- 24 months
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: "Expression of retinoid-X receptors (-alpha,-beta,-gamma) and retinoic acid receptors (-alpha,-beta,-gamma) in normal human skin: an immunohistological evaluation." dans: The Histochemical journal, Vol. 29, Issue 2, pp. 127-33, (1997) (PubMed).
: "Detection of retinoid X receptors using specific monoclonal and polyclonal antibodies." dans: Biochemical and biophysical research communications, Vol. 204, Issue 2, pp. 525-36, (1994) (PubMed).
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- Retinoid X Receptor gamma (RXRG) (Retinoid X Receptor, gamma (RXRG))
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Autre désignation
- RXR-gamma
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Sujet
- RXR-g (retinoid X receptor gamma, NR2B3) is a member of the nuclear receptors superfamily, specifically those involved in mediating the effects of retinoic acid (RA). This receptor forms heterodimers with the RAR (retinoic acid receptor), TR (thyroid hormone receptor) and the VDR (vitamin D receptor), increasing both DNA binding and transcriptional function on their respective response elements.
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Poids moléculaire
- 51 kDa
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ID gène
- 20183
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NCBI Accession
- NP_033133
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Pathways
- Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
Antigène
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