MEIS1/MEIS2/MEIS3 (AA 50-390) anticorps

N° du produit ABIN2668724

Cité dans 3 publications. Cet anticorps anti-MEIS1/MEIS2/MEIS3 Monoclonal Souris (Clone 9-2-7) (ABIN2668724) détecte spécifiquement MEIS1/MEIS2/MEIS3 dans ICC et IF. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour MEIS1/MEIS2/MEIS3 (AA 50-390) anticorps (ABIN2668724)

Antigène: MEIS1/MEIS2/MEIS3

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Immunocytochemistry (ICC), Immunofluorescence (IF)

Clone: 9-2-7

Détail du produit

Épitope: AA 50-390

Fonction: MEIS 1/2/3 antibody (mAb) (Clone 9.2.7)

Purification: Protein A Chromatography

Immunogène: This MEIS antibody was raised against a recombinant protein corresponding to amino acids amino acids 50-390 mouse MEIS1.

Isotype: IgG1

Information d'application

Indications d'application: ICC/IF: 0.5 μg/mL dilution This antibody is also available as an AbFlex engineered recombinant antibody. For details on the corresponding AbFlex Recombinant Antibody, see Catalog No. 91259.

Restrictions: For Research Use only

Stockage

Concentration: 1 μg/μL

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Stock: -20 °C

Stockage commentaire: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Date de péremption: 24 months

Référence

Przepiorski, Vanichapol, Espiritu, Crunk, Parasky, McDaniels, Emlet, Salisbury, Happ, Vernetti, MacDonald, Kellum, Kleyman, Baty, Davidson, Hukriede: "Modeling oxidative injury response in human kidney organoids." dans: Stem cell research & therapy, Vol. 13, Issue 1, pp. 76, (2022) (PubMed).

Hilliard, Yao, El-Dahr: "Mdm2 is required for maintenance of the nephrogenic niche." dans: Developmental biology, Vol. 387, Issue 1, pp. 1-14, (2014) (PubMed).

Shim, Kim, Shin, Kim, Park: "Regulation of EphA8 gene expression by TALE homeobox transcription factors during development of the mesencephalon." dans: Molecular and cellular biology, Vol. 27, Issue 5, pp. 1614-30, (2007) (PubMed).

Détail du antigène

Antigène: MEIS1/MEIS2/MEIS3

Autre désignation: MEIS 1/2/3

Sujet: The MEIS family or proteins (Myeloid Ecotropic viral Integration Site homologues) encode proteins that function as cofactors for the Homeobox (HOX) proteins. Homeobox genes play a crucial role in normal development. In addition, several homeoproteins are involved in neoplasia. MEIS and a functionally related protein Pbx belong to the TALE (Three Amino acid Loop Extension) homeodomain superfamily of proteins. The role of MEIS proteins in the regulation of transcription is as yet unclear.

Poids moléculaire: 54-66 kDa

ID gène: 4211

NCBI Accession: NP_034919