MAZ anticorps

N° du produit ABIN2668733

Cité dans 2 publications. Cet anticorps anti-MAZ Monoclonal Souris (Clone 133) (ABIN2668733) détecte spécifiquement MAZ dans WB, ChIP et SSA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour MAZ anticorps (ABIN2668733)

Antigène: MAZ (MYC-Associated Zinc Finger Protein (Purine-Binding Transcription Factor) (MAZ))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MAZ est non-conjugé

Application: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP), Supershift Assay (SSA)

Clone: 133

Détail du produit anti-MAZ anticorps

Fonction: MAZ antibody (mAb) (Clone 133)

Purification: Protein G Chromatography

Immunogène: This MAZ antibody was raised against recombinant human MAZ protein.

Isotype: IgG

Information d'application

Indications d'application: WB This antibody is also available as an AbFlex engineered recombinant antibody. For details on the corresponding AbFlex Recombinant Antibody, see Catalog No. 91205.

Restrictions: For Research Use only

Stockage

Concentration: 1 μg/μL

Buffer: Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Stock: -20 °C

Stockage commentaire: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Date de péremption: 24 months

Références pour anticorps anti-MAZ (ABIN2668733)

Himeda, Ranish, Hauschka: "Quantitative proteomic identification of MAZ as a transcriptional regulator of muscle-specific genes in skeletal and cardiac myocytes." dans: Molecular and cellular biology, Vol. 28, Issue 20, pp. 6521-35, (2008) (PubMed).

Ashfield, Patel, Bossone, Brown, Campbell, Marcu, Proudfoot: "MAZ-dependent termination between closely spaced human complement genes." dans: The EMBO journal, Vol. 13, Issue 23, pp. 5656-67, (1995) (PubMed).

Détails sur MAZ

Antigène: MAZ (MYC-Associated Zinc Finger Protein (Purine-Binding Transcription Factor) (MAZ))

Autre désignation: Maz

Sujet: MAZ (Myc-associated zinc finger protein) functions as a transcription factor roles in both transcription initiation and termination. MAZ binds to two sites within the c-Myc promoter, ME1a1 and ME1a2. It also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors. MAZ also participates in skeletal muscle development through the activation of several skeletal muscle-specific genes. MAZ has also been reported to drive tumor-specific expression of PPAR-gamma in breast cancer cells.

Poids moléculaire: 55 kDa

ID gène: 4150

NCBI Accession: NP_002374

Pathways: Chromatin Binding