EED anticorps

N° du produit ABIN2668749

Cet anticorps Souris Monoclonal détecte spécifiquement EED dans WB, IHC, ChIP-seq et ChIP. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour EED anticorps (ABIN2668749)

Antigène: EED (Embryonic Ectoderm Development (EED))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp EED est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ChIP DNA-Sequencing (ChIP-seq), Chromatin Immunoprecipitation (ChIP)

Clone: 41D

Détail du produit anti-EED anticorps

Fonction: EED antibody (mAb) (Clone 41D)

Purification: Protein A Chromatography

Immunogène: This EED antibody was raised against full-length recombinant human EED protein.

Isotype: IgG2a

Information d'application

Indications d'application: ChIP: 4 µL per ChIP ChIP-Seq: 4 µL each IHC: 2 - 8 μg/mL dilution This antibody is also available as an AbFlex engineered recombinant antibody. For details on the corresponding AbFlex Recombinant Antibody, see Catalog No. 91135.

Restrictions: For Research Use only

Stockage

Concentration: 1 μg/μL

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Stock: -20 °C

Stockage commentaire: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Date de péremption: 24 months

Détails sur EED

Antigène: EED (Embryonic Ectoderm Development (EED))

Autre désignation: EED

Sujet: EED (extraembryonic ectoderm) is a component of the Polycomb group (PcG) multiprotein complex PRC2. The PRC2 complex also contains EZH2 and SUZ12 and is recruited to Polycomb response elements and results in the methylation of histone H3 and lysine 27 and the silencing of gene expression. PRC2 initiates repression of the Hox genes during development and is involved in the maintenance of stem cell pluripotency. EED is a member of the superfamily of WD-40 repeat protein family and is required for PRC2-mediated H3K27 methylation. The PRC2 complex may also recruit platform DNMTs, thereby linking two systems of epigenetic repression.

Poids moléculaire: 57 kDa

ID gène: 8726

NCBI Accession: NP_003788