CARM1 anticorps (C-Term)

N° du produit ABIN2668761

Cet anticorps Lapin Polyclonal détecte spécifiquement CARM1 dans WB, IHC, IP et ChIP. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.Il a été cité dans 1 publication.

Aperçu rapide pour CARM1 anticorps (C-Term) (ABIN2668761)

Antigène: CARM1 (Coactivator-Associated Arginine Methyltransferase 1 (CARM1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CARM1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Chromatin Immunoprecipitation (ChIP)

Détail du produit anti-CARM1 anticorps

Épitope: C-Term

Fonction: CARM1 antibody (pAb)

Purification: Unpurified

Immunogène: This CARM1 antibody was raised against a peptide corresponding to the C-terminus of mouse CARM1.

Information d'application

Indications d'application: WB: 1:250 - 1:1,000 dilution The addition of 0.05 % Tween 20 in the blocking buffer and primary antibody incubation buffer is recommended to aid in detection by Western blot. Individual optimization may be required.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit serum containing 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Stock: -20 °C

Stockage commentaire: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Date de péremption: 24 months

Références pour anticorps anti-CARM1 (ABIN2668761)

Mann, Cortez, Vadlamudi: "PELP1 oncogenic functions involve CARM1 regulation." dans: Carcinogenesis, Vol. 34, Issue 7, pp. 1468-75, (2013) (PubMed).

Détails sur CARM1

Antigène: CARM1 (Coactivator-Associated Arginine Methyltransferase 1 (CARM1))

Autre désignation: CARM1

Sujet: CARM1 (Coactivator-associated arginine methyltransferase 1 or CARM 1) is a protein arginine N-methyltransferase that catalyzes the mono- and asymmetric dimethylation of arginine residues in its substrate proteins. It serves as a coactivator of transcription and also plays a role in nuclear receptors. CARM1 methylates histone H3 at Arg2, Arg17 and Arg26, it also methylates a number of non-histone substrates involved in the regulation and mechanism of gene expression.

Poids moléculaire: 60 kDa

ID gène: 10498

NCBI Accession: NP_067506

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of fat Cell Differentiation